Orally administered medical device for the safe reduction of blood sugar levels without uptake into the body
About SiPore®
The Company’s lead product candidate, SiPore®, is an orally-administered medical device for the safe reduction of blood sugar levels in people at risk of developing diabetes, prediabetics, and newly diagnosed type 2 diabetics. The device is a tasteless and odourless white powder taken with water. A First in Man clinical trial of SiPore® showed significant reductions in a range of metabolic parameters and an excellent safety profile. SiPore® has undergone clinical testing confirming its safety and performance.
Watch our video on how SiPore® has been created to lower blood sugar levels.
About SiPore®
The Company’s lead product candidate, SiPore®, is an orally-administered medical device for the safe reduction of blood sugar levels in people at risk of developing diabetes, prediabetics, and newly diagnosed type 2 diabetics. The device is a tasteless and odourless white powder taken with water. A First in Man clinical trial of SiPore® showed significant reductions in a range of metabolic parameters and an excellent safety profile. SiPore® has undergone clinical testing confirming its safety and performance.
Watch our video on how SiPore® has been created to lower blood sugar levels.
How SiPore® works
SiPore® has been developed with optimal safety in mind. Designed to act locally in the gut, the device consists of precisely engineered micron-sized silica particles with tailored porosity. Inside the gut, the particles work as a molecular sieve by mechanically separating digestive enzymes from undigested food, thereby improving metabolic health through a gentle mode of action. The particles pass through the body without being absorbed and are safely eliminated in the same manner as food.
Extensive preclinical studies and clinical development in-house and in collaboration with external research groups clearly demonstrate the safety and performance of SiPore®.
”SiPore® is designed with safety and sustainability in mind. It is made of pure silica, a natural mineral made of silicon and oxygen, two of the earth’s most abundant elements. SiPore® derives its function from its unique architecture and chemistry. It is gentle to the human body as to the environment.
Dr. Eric JohnstonCTO & Inventor
Intellectual property
Sigrid Therapeutics has five patent families covering the SiPore® technology’s use in several clinical indications, its use in oral health, New Chemical Entity patent applications with compositional matter for SiPore® and formulations incorporating the SiPore® technology. The Company has granted patents in key territories and holds global rights to all patents and patent applications.
Intellectual property
Sigrid Therapeutics has two patent families covering the SiPore® technology and its use in several clinical indications, and New Chemical Entity patent applications with compositional matter for SiPore®. The Company has granted patents in key territories and holds global rights to all patents and patent applications.
Sigrid also relies on know-how and trade secrets for our material production and on continuing technological innovation to develop and maintain our proprietary position on the market.