SiPore®

Orally administered medical device for the safe reduction of blood sugar levels without uptake into the body

About SiPore®

The Company’s lead product candidate, SiPore®, is an orally-administered medical device for the safe reduction of blood sugar levels in people at risk of developing diabetes, prediabetics, and newly diagnosed type 2 diabetics. The device is a tasteless and odourless white powder taken with water. A First in Man clinical trial of SiPore® showed significant reductions in a range of metabolic parameters and an excellent safety profile. SiPore® has undergone clinical testing confirming its safety and performance.

Watch our video on how SiPore® has been created to lower blood sugar levels.

Read about STAR

About SiPore®

The Company’s lead product candidate, SiPore®, is an orally-administered medical device for the safe reduction of blood sugar levels in people at risk of developing diabetes, prediabetics, and newly diagnosed type 2 diabetics. The device is a tasteless and odourless white powder taken with water. A First in Man clinical trial of SiPore® showed significant reductions in a range of metabolic parameters and an excellent safety profile. SiPore® has undergone clinical testing confirming its safety and performance.

Watch our video on how SiPore® has been created to lower blood sugar levels.

Read about STAR

How SiPore® works

SiPore® has been developed with optimal safety in mind. Designed to act locally in the gut, the device consists of precisely engineered micron-sized silica particles with tailored porosity. Inside the gut, the particles work as a molecular sieve by mechanically separating digestive enzymes from undigested food, thereby improving metabolic health through a gentle mode of action. The particles pass through the body without being absorbed and are safely eliminated in the same manner as food.

Extensive preclinical studies and clinical development in-house and in collaboration with external research groups clearly demonstrate the safety and performance of SiPore®.

Read about prediabetes

SiPore® is designed with safety and sustainability in mind. It is made of pure silica, a natural mineral made of silicon and oxygen, two of the earth’s most abundant elements. SiPore® derives its function from its unique architecture and chemistry. It is gentle to the human body as to the environment.

Dr. Eric JohnstonCTO & Inventor

Intellectual property

Sigrid Therapeutics has two patent families covering the SiPore® technology and its use in several clinical indications, and New Chemical Entity patent applications with compositional matter for SiPore®. The Company has granted patents in key territories and holds global rights to all patents and patent applications.

Sigrid also relies on know-how and trade secrets for our material production and on continuing technological innovation to develop and maintain our proprietary position on the market.

See what's in our Pipeline

Intellectual property

Sigrid Therapeutics has two patent families covering the SiPore® technology and its use in several clinical indications, and New Chemical Entity patent applications with compositional matter for SiPore®. The Company has granted patents in key territories and holds global rights to all patents and patent applications.

Sigrid also relies on know-how and trade secrets for our material production and on continuing technological innovation to develop and maintain our proprietary position on the market.

See what's in our Pipeline